Product Description
| Name |
Sonwu Supply Cabozantinib Malate Intermediate Powder Cabozantinib Malate |
| CAS NO. |
1140909-48-3 |
| Molecular Formula |
C32H30FN3O10 |
| MW |
635.59300 |
| Purity |
99% |
| Appearanc |
White powder |
| Certificate |
ISO, SGS, GMP, HACCP |
| MOQ |
10 g |
| Shelf life |
2 Years |
Cabozantinib is a small molecule C-Met modulator. Cabozantinib acts as a potent multitargeted VEGFR2, Met, FLT3, Tie2, Kit and Ret inhibitor with IC50 of 0.035, 1.8, 14.4, 14.3 and 4.6 nM for VEGFR2, Met, FLT3, Tie2 and Kit, respectively.
Cabozantinib malate is the malate of Cabozantinib, a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively.
Detailed Photos
Certifications
Functions
Cabozantinib Malate should be stored in a well-closed container at low temperature, keep away from moisture, heat and light.
Cabozantinib (marketed under the tradename Cometriq, formerly known as XL184) is a potent VEGFR2 inhibitor with IC50 of 0.035 nM. XL-184 also displays potent activity against Met, Ret, Kit, FLT1, FLT3, FLT4, Tie2, and AXL. XL184 at low concentration(0.1-0.5 μM) is sufficient to induce marked inhibition of constitutive and inducible Met phosphorylation and its resultant downstream signaling in MPNST cells, and inhibit HGF-induced MPNST cell migration and invasion.
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OEM Service
HARD CAPSULE
Type: 0# 1# 2# 3#
Color: More than 30 colors are available.
Capsules have a hard shell, and either contain powders or dry ingredients. Suitable for all kinds of plant extract powder.
TABLET
Type: 250mg 500mg 1000mg 2000mg
Professional Mould, Provide you tablets of various shapes.
Tablets are a harder dosage form compared to softgels and capsules. Suitable for all kinds of plant extract powder.
SOFTGEL
Model: 500mg 1000mg 2000mg...
Softgels have a gelatin shell, surrounding a gel or liquid interior.Suitable for all kinds of animal and plant essential oils.
BOTTLE
Type: PET, PE(HDPE),....
Volume:60cc,120cc, 150cc, 200cc, 250cc...
Customized size,color and label design are available.
SMALL BAG PACKAGE
Type: 10g, 50g, 100g, 500g, 1000g, 2000g...
Small bag is also a good choice for a small amount of contents packaged.Customized size,color and label design are available.
Packaging & Shipping
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FAQ
1. Customs clearance
1) By Express:
Normally there is no special need for the recipient to clear the customs. If the customs has an objection,our rich experienced and professional group will help you clear the customs.
2) By Air and by Sea:
Our company will cooperate with the recipient to provide relevant file and information in the customs clearance procedure.
2. Payment
T/T,Western Union,MoneyGram,Trade Assurance Order,L/C etc.
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