Product Description
Product Name |
Taurochenodeoxycholic Acid |
CAS |
516-35-8 |
MF |
C26H45NO4 |
MW |
499.704 |
MOQ |
50g |
Test Method |
HPLC |
Purity |
99% |
Appearance |
White Crystalline Powder |
Shelf Life |
2 Years |
Storage |
Cool and Dry Place |
Taurochenodeoxycholic acid (TCDCA) is a bile acid that is synthesized in the liver and secreted into bile. It is a secondary bile acid formed from the conversion of chenodeoxycholic acid (CDCA) in the gut by the bacterial enzyme TCD bile and has been shown to play a role in lipid metabolism and cholesterol homeostasis.
TCDCA acts as a cleanser, helping to emulsify fats and facilitate their absorption in the gut. It also activates receptors in the liver and other tissues that regulate lipid and glucose metabolism.
It is used as a diagnostic marker for liver diseases such as cholestasis, in which bile flow is reduced due to impaired liver function. It is also used to study the effects of bile acids on lipid and glucose metabolism, and for drug development to treat metabolic disorders and liver diseases.
Certifications
Application
1. Cholestasis treatment: TCDCA can be used as a drug for the treatment of cholestasis. It can help promote bile secretion and excretion, thereby alleviating diseases caused by cholestasis.
2. Research on bile acid metabolism: TCDCA is a commonly used marker of bile acid metabolism. Researchers can use TCDCA to track the metabolism and transport of bile acids.
3. Liver disease research: TCDCA can be used to study the pathogenesis of liver diseases, such as liver fibrosis and cirrhosis.
4. Gut microbiome research: TCDCA can be used as a substrate in gut microbiome research. It can be metabolized by gut microbes and produce other beneficial substances.
5. Cholelithiasis research: TCDCA can be used to study the pathogenesis and treatment of cholelithiasis.
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Tauroursodeoxycholate |
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