Customization: | Available |
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Type: | Amino Acid |
Chemical Character: | Acidity |
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Product Name | 5-Aminolevulinic acid hydrochloride |
CAS | 5451-09-2 |
MF | C5H10ClNO3 |
EINECS | 226-679-5 |
Appearance | White powder |
5- aminolevulinic acid hydrochloride is mainly used as the substrate of 5- aminolevulinate dehydrogenase, biochemical research.
5-aminolevulinic acid hydrochloride is a natural amino acid; As a precursor of tetrapyrrole, it is used in the biosynthesis of chlorophyll and heme. Anti - tumor drugs (photosensitizers).
5-aminolevulinic acid significantly reduced glutamate uptake by K (m) and V(Max), indicating non-competitive inhibition. In astrocytes cultured under these conditions, 5-aminolevulinic acid significantly increased lipid peroxidation in astrocytes. 5-aminolevulinic acid-mediated sonodynamic therapy demonstrated synergistic apoptosis of THP-1 macrophages, involving excessive intracellular reactive oxygen species production and MMP loss.