| Customization: | Available |
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| Powder: | Yes |
| Customized: | Customized |
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Chenodeoxycholic acid is a bile acid. Salts of this carboxylic acid are called Chenodeocycholates. Chenodeoxycholic acid is one of the main bile acids. It was first isolated from the bile of the domestic goose, which gives it the "cheno" portion of its name.
Chenodeoxycholic acid and cholic acid are the two primary bile acids in humans. Chenodeoxycholic acid has two hydroxyl groups and is modified with the addition of another hydroxyl group to produce cholic acid. Some other mammals have muricholic acid or deoxycholic acid rather than chenodeoxycholic acid. It occurs as a white crystalline substance insoluble in water but soluble in alcohol and acetic acid, with melting point at 165-167 °C.
Chenodeoxycholic acid is synthesized in the liver from cholesterol via several enzymatic steps. Like other bile acids, it can be conjugated with taurine or glycine, forming taurochenodeoxycholate or glycochenodeoxycholate. Conjugation results in a lower pKa. This results in the conjugated bile acids being ionized at the usual pH in the intestine, and staying in the gastrointestinal tract until reaching the ileum to be reabsorbed.
CDCA and other bile acids form micelles, which facilitate lipid digestion. After absorption, they are taken up by the liver and resecreted, so undergoing an enterohepatic circulation. Unabsorbed CDCA can be metabolised by bacteria in the colon to form the secondary bile acid, lithocholic acid or the epimer, ursodeoxycholic acid.
CDCA is the most potent natural bile acid at stimulating the nuclear bile acid receptor, farnesoid X receptor (FXR).The transcription of many genes is activated by FXR, including FGF19 and SHP.
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HARD CAPSULE
Type: 0# 1# 2# 3# Coulor: More than 30 colours are available. Capsules have a hard shell, and either contain powders or dry ingredients. Suitable for all kinds of plant extract powder. |
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TABLET
Type: 250mg 500mg 1000mg 2000mg Professional Mould, Provide you tablets of various shapes. Tablets are a harder dosage form compared to softgels and capsules. Suitable for all kinds of plant extract powder. |
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SOFTGEL
Softgels have a gelatin shell, surrounding a gel or liquid interior.Suitable for all kinds of animal and plant essential oils. |
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BOTTLE
Volume:60cc,120cc, 150cc, 200cc, 250cc...
Customized size,color and label design are available. |
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SMALL BAG PACKAGE Type: 10g, 50g, 100g, 500g, 1000g, 2000g... Small bag is also a good choice for a small amount of contents packaged.Customized size,color and label design are available. |
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