• Sonwu Supply CAS 943319-70-8 Ponatinib Powder Ponatinib
  • Sonwu Supply CAS 943319-70-8 Ponatinib Powder Ponatinib
  • Sonwu Supply CAS 943319-70-8 Ponatinib Powder Ponatinib
  • Sonwu Supply CAS 943319-70-8 Ponatinib Powder Ponatinib
  • Sonwu Supply CAS 943319-70-8 Ponatinib Powder Ponatinib
  • Sonwu Supply CAS 943319-70-8 Ponatinib Powder Ponatinib

Sonwu Supply CAS 943319-70-8 Ponatinib Powder Ponatinib

Powder: Yes
Customized: Customized
Certification: GMP, HSE, ISO 9001, USP, BP, SGS
Suitable for: Adult
State: Powder
Purity: 99%
Samples:
US$ 40/gram 1 gram(Min.Order)
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Customization:
Manufacturer/Factory
Diamond Member Since 2021

Suppliers with verified business licenses

Rating: 5.0/5
Shaanxi, China
Importers and Exporters
The supplier has import and export rights
Years of Export Experience
The export experience of the supplier is more than 10 years
Experienced Team
The supplier has 6 foreign trading staff(s) and 2 staff(s) with over 6 years of overseas trading experience
Fast Delivery
The supplier can deliver the goods within 15 days
to see all verified strength labels (6)
  • Overview
  • Product Description
  • Detailed Photos
  • Functions
  • Recommended products
  • OEM Service
  • Packaging & Shipping
  • Feedbacks
  • FAQ
Overview

Basic Info.

Model NO.
SWP A214-1
Type
Ponatinib
Grade
Pharmaceutical
Appearance
White Powder
CAS
943319-70-8
Mf
C29h27f3n6o
MW
532.56
MOQ
5 G
Test Method
HPLC
Shelf Life
2 Years
Transport Package
Drum, Vacuum Packed
Specification
5 g/bag
Trademark
Sonwu
Origin
Shaanxi, China
Production Capacity
500kg/Month

Product Description


Sonwu Supply CAS 943319-70-8 Ponatinib Powder Ponatinib
Product Description
Product Name Sonwu Supply CAS 943319-70-8 Ponatinib Powder Ponatinib
CAS NO. 943319-70-8
MF C29H27F3N6O
MW 532.56
Density 1.3±0.1 g/cm3
Appearance White Powder
Certificate ISO, SGS, GMP, HACCP
Assay Method HPLC
Extraction Type Solvent Extraction
Sample Available
MOQ 5g
Shelf life 2 Years
Storage Store in cool & dry place not freeze
Keep away from strong light and heat
 

Ponatinib is an oral bioavailable multi-target receptor tyrosine kinase (RTK) inhibitor with potential anti-angiogenesis and anti-disease activities.

Ponatinib is a protein kinase inhibitor, for example, chronic myeloid leukemia (CML) and Philadelphia chromosome positive acute lymphoblastic leukemia (Ph+ ALL).

 

Detailed Photos

Sonwu Supply CAS 943319-70-8 Ponatinib Powder Ponatinib

Functions



1.  Panatinib successfully suppressed the function of the BCR-ABL mutation in patients with refractory chronic myelogenous leukemia in a phase I clinical trial.

2. Panatinib not only inhibits BCR-ABL itself and its mutants at an effective concentration in clinical practice, but also inhibits FLT3 Kit in vitro FGFR1 and PDGFR alpha activity, with containing these receptors active forms of leukemia cell line experiment, we find that it can effectively inhibit receptor phosphorylation and cell proliferation, in patients with acute myeloid leukemia, for he are activated to restrain activity of FLT3 - ITD mutants of 30%, in MV4-11 (FLT3 ITD + / +) in acute myeloid leukemia cells, the, for, in less than 10 nmol/L concentrations can inhibit FLT3 signal and the induction of apoptosis.

3. Ponatinib inhibited all of the BCR-ABL mutant strains in the assay, and BCR-ABT315I inhibited bad cells in mice. 


4. Ponatinib is an antidisease product. It was approved by FDA in December 2012 for adult chronic myelogenous leukemia (CML) and "Philadelphia chromosome positive" (PH +) acute lymphoblastic leukemia (ALL).

5. Ponatinib was approved in the European Union in July 2013 through a centralised approval process. Panatinib is the third generation of multi-target tyrosine kinase inhibitors. Typical api of multi-target tyrosine kinase inhibitors include sunitinib, imatinib, sorafenib and vataranib., for he (Ponatinib) can effectively inhibit the in vitro FGFR1-4 kinase activity, its IC50 alue concentration,2,18 2 and 8 nmol/L respectively, in the absence of interleukin - 3 cells, FGFR1, on behalf of, to curb cells - 4 kinase expression of IC50 alue concentration were 8 August 24 and 34 nmol/L, and tested in each cell, for inhibition of FGFR1-4 phosphorylation, its IC50 alue concentration is 39 29 32 and 39 nmol/L respectively tested on endometrial bladder Stomach and thymus in multiple cell lines FGFR inhibition.

 

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OEM Service
Sonwu Supply CAS 943319-70-8 Ponatinib Powder Ponatinib
HARD CAPSULE

 
Type: 0# 1# 2# 3#

Color: More than 30 colors are available.
Capsules have a hard shell, and either contain powders or dry ingredients. Suitable for all kinds of plant extract powder.
TABLET

 
Type: 250mg 500mg 1000mg 2000mg
Professional Mould, Provide you tablets of various shapes.
Tablets are a harder dosage form compared to softgels and capsules. Suitable for all kinds of plant extract powder.
Sonwu Supply CAS 943319-70-8 Ponatinib Powder Ponatinib
Sonwu Supply CAS 943319-70-8 Ponatinib Powder Ponatinib
BOTTLE

 
Type: PET, PE(HDPE),....
Volume:60cc,120cc, 150cc, 200cc, 250cc...
Customized size,color and label design are available.
SMALL BAG PACKAGE


Type: 10g, 50g, 100g, 500g, 1000g, 2000g...

Small bag is also a good choice for a small amount of contents packaged.Customized size,color and label design are available.
Sonwu Supply CAS 943319-70-8 Ponatinib Powder Ponatinib
Packaging & Shipping

Sonwu Supply CAS 943319-70-8 Ponatinib Powder Ponatinib

Feedbacks
Sonwu Supply CAS 943319-70-8 Ponatinib Powder Ponatinib
FAQ
Sonwu Supply CAS 943319-70-8 Ponatinib Powder Ponatinib
1. Customs clearance
1) By Express:
Normally there is no special need for the recipient to clear the customs. If the customs has an objection,our rich experienced and professional group will help you clear the customs.
2) By Air and by Sea:
Our company will cooperate with the recipient to provide relevant file and information in the customs clearance procedure.
2. Payment
T/T,Western Union,MoneyGram,Trade Assurance Order,L/C etc.

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Diamond Member Since 2021

Suppliers with verified business licenses

Rating: 5.0/5
Manufacturer/Factory
Management System Certification
ISO 9001, ISO 9000, ISO 14001, ISO 14000, ISO 20000, HSE, ISO 14064, QC 080000, GMP