Sonwu Supply Pharmaceutical Powder Regorafenib

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: SWP A215
• Certification: GMP, HSE, ISO 9001, USP, BP, SGS
• Suitable for: Adult
• State: Powder
• Purity: 99%
• Type: Regorafenib
• Grade: Pharmaceutical
• Appearance: White Powder
• CAS: 755037-03-7
• Mf: C21h15clf4n4o3
• MW: 482.82
• MOQ: 5 G
• Test Method: HPLC
• Shelf Life: 2 Years
• Transport Package: Drum, Vacuum Packed
• Specification: 5 g/bag
• Trademark: Sonwu
• Origin: Shaanxi, China
• Production Capacity: 500kg/Month

Product Description

Product Description

Product Name	Sonwu Supply Pharmaceutical Powder Regorafenib
CAS NO.	755037-03-7
MF	C21h15clf4n4o3
MW	482.82
Appearance	White Powder
Certificate	ISO, SGS, GMP, HACCP
Assay Method	HPLC
Extraction Type	Solvent Extraction
Sample	Available
MOQ	5g
Shelf life	2 Years
Storage	Store in cool & dry place not freeze Keep away from strong light and heat

 

Regorafenib (BAY 73-4506, commercial name Stivarga) is an oral multi-kinase inhibitor developed by Bayer which targets angiogenic, stromal and oncogenic receptor tyrosine kinase (RTK). Regorafenib shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition. Since 2009 it was studied as a potential treatment option in multiple tumor types.[1] By 2015 it had 2 US approvals for advanced cancers.

 

Detailed Photos

Functions

1. Regorafenib targets both tumor cell proliferation and tumor vasculature through inhibition of receptors of tyrosine kinases (VEGFR, KIT, RET, FGFR, and PDGFR) and serine/threonine kinases (Raf and p38MAPK). Regorafenib suppresses growth of human Hep3B, PLC/PRF/5 and HepG2 cells in a concentration- and time-dependent manner.

2. Regorafenib reveals potent dose-dependent TGI in various preclinical human xenograft models in mice, with tumor shrinkages in breast MDA-MB-231 and renal 786-O carcinoma models. Regorafenib prevents not only the growth of syngeneic primary 4T1 breast tumors growing orthotopically in the fat pad, but also suppresses the formation of tumor metastasis in the lung.

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OEM Service

HARD CAPSULE

 

Type: 0# 1# 2# 3#

Color: More than 30 colors are available.
Capsules have a hard shell, and either contain powders or dry ingredients. Suitable for all kinds of plant extract powder.

TABLET

 

Type: 250mg 500mg 1000mg 2000mg
Professional Mould, Provide you tablets of various shapes.
Tablets are a harder dosage form compared to softgels and capsules. Suitable for all kinds of plant extract powder.

BOTTLE

 

Type: PET, PE(HDPE),....

Volume:60cc,120cc, 150cc, 200cc, 250cc...
Customized size,color and label design are available.

SMALL BAG PACKAGE


Type: 10g, 50g, 100g, 500g, 1000g, 2000g...

Small bag is also a good choice for a small amount of contents packaged.Customized size,color and label design are available.

Packaging & Shipping

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FAQ

1. Customs clearance

1) By Express:

Normally there is no special need for the recipient to clear the customs. If the customs has an objection,our rich experienced and professional group will help you clear the customs.

2) By Air and by Sea:

Our company will cooperate with the recipient to provide relevant file and information in the customs clearance procedure.

2. Payment

T/T,Western Union,MoneyGram,Trade Assurance Order,L/C etc.