| Customization: | Available |
|---|---|
| Certification: | RoHS, ISO, HACCP, SGS |
| Assay Method: | HPLC |
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| Product Name | Sonwu Supply Artesunate Herbal Extract Artesunate |
| Specification | 99% |
| Cas NO. | 88495-63-0 |
| Density | 1.31 |
| Molecular Formula | C19H28O8 |
| Molecular Weight | 384.425 |
| Refractive index | 1.543 |
| Appearance | White Powder |
| Certificate | ISO, SGS, GMP, HACCP |
| Assay Method | HPLC |
| Extraction Type | Solvent Extraction |
| Sample | Available |
| MOQ | 100g |
| Shelf life | 2 Years |
| Storage | Store in cool & dry place not freeze Keep away from strong light and heat |
Artesunate is used primarily for malaria; it has also been shown to be >90% efficacious at reducing egg production in Schistosoma haematobium infection. According to WHO intravenous AS is the choice for severe malaria both in children and adults where there is low transmission.In regions where transmission is high, randomized trials among Asian adults and African children strongly advocates the use of artesunate over quinine as the choice for falciparum malaria. Artesunate is prepared from dihydroartemisinin (DHA) by reacting it with succinic acid anhydride in basic medium. As base/solvent, sodium bicarbonate and catalyst DMAP have been used, with yields of up to 100%. A large scale process involves overcomeing DHA with a mixture, a catalytic amount of DMAP and succinic anhydride. The mixture is stirred for 6-9 h to get artesunate in quantitative yield. The product is further re-crystallized. alpha-Artesunate is exclusively formed (m.p 135-137C).
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