Product Description
| Name |
Gefitinib |
| CAS NO. |
184475-35-2 |
| Molecular Formula |
C22h24clfn4o3 |
| MW |
446.9 |
| Purity |
99% |
| Appearanc |
White powder |
| Certificate |
ISO, SGS, GMP, HACCP |
| MOQ |
10 g |
| Shelf life |
2 Years |
Gefitinib, is used for certain breast, lung , and other diseases, also known as Iressa, a selective EGFR tyrosine kinase inhibitor, for prior locally advanced or metastatic non-chemical or unsuitable for chemotherapysmall cell lung disease (NSCLC).
Gefitinib is the first molecular targeted to be used in non-small cell lung disease. EGF are a kind of polypeptide with a relative molecular mass of 6.45x103, and they can bind with EGFR on target cell membrane surfaces to trigger biological effects. EGFR is a type of tyrosine kinase (TK) type receptor, so when bound with EGF, it will promote TK activation in the receptor. This will cause tyrosine residue in the receptor to autophosphorylate and send continuous dividing signals into the cell, causing cell proliferation and differentiation. EGFR is abundant in human tissue, and it is highly expressed in malign cells.
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Functions
Gefitinib blocks the signal transduction pathway of cell surface EGFR to prevent bad cell growth, metastasis, and growth in blood vessels, and it can induce bad cell apoptosis. Gefitinib is mainly used for non-stem cell lung disease.
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HARD CAPSULE
Type: 0# 1# 2# 3#
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Capsules have a hard shell, and either contain powders or dry ingredients. Suitable for all kinds of plant extract powder.
TABLET
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Professional Mould, Provide you tablets of various shapes.
Tablets are a harder dosage form compared to softgels and capsules. Suitable for all kinds of plant extract powder.
SOFTGEL
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Softgels have a gelatin shell, surrounding a gel or liquid interior.Suitable for all kinds of animal and plant essential oils.
BOTTLE
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Small bag is also a good choice for a small amount of contents packaged.Customized size,color and label design are available.
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