Customization: | Available |
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Powder: | Yes |
Customized: | Customized |
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LarotRectiniB (LOXO-101) is an ATP competitive, oral selective inhibitor, three subtypes (TRKA, B and C) of the original maternal condensation kinase (TRK) family receptor with NaMole level 50% inhibitory concentration.
The proliferation measurement processed by LAROTRECTINIB (LOXO-101) indicates the dose-dependent inhibition of cell proliferation in all three cell lines. For Cuto-3.29, IC50 is less than 100 nm, for KM12 and MO-91, IC50 less than 10 nm, which is consistent with the known efficacy of the TRK kinase family.
Dasatinib | AZD9291 | Lapatinib ditosylate | Erlotinib Hydrochloride |
Gefitinib | Niraparib tosylate monohydrate | Imatinib mesylate | Imatinib |
LOXO 195 | Lapatinib | Ibrutinib | Cabozantinib Malate |
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