| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
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Potent precision of the second generation of tyrosine kinase inhibitors, effective therapy for pharmaceutical resistance or intolerance of patients with chronic myeloid leukemia.Nilotinib in the form of the hydrochloride monohydrate salt, is a small-molecule tyrosine kinase inhibitor approved for the therapy of imatinib-resistant chronic myelogenous leukemia.Structurally related to imatinib, it was developed based on the structure of the Abl-imatinib complex to address imatinib intolerance and resistance. Nilotinib is a selective Bcr-Abl kinase inhibitor that is 10-30 fold more potent than imatinib in inhibiting Bcr-Abl tyrosine kinase activity and proliferation of Bcr-Abl expressing cells.
| Product name | Nilotinib |
| Other name | Nilotinib |
| Appearance | White powder |
| Specification | 99% |
| CAS No. | 641571-10-0 |
| EINECS | 700-544-5 |
| M F | C28H22F3N7O |
| MW | 529.51600 |
| Melting point | 231-233 °C |
| Mol | 641571-10-0.mol |
| Test method | HPLC |
A powerful and precise second-generation tyrosine kinase inhibitor, effective in solvting patients with intolerant chronic myelogenous leukemia.
Nilotinib is an antineoplasm pharmaceutical, and it is mainly used clinically to solve chronic myelogenous leukemia that is resistant to Gleevec (imatinib).
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